An abnormally operating bone marrow can be found in conditions such as aplastic anemia, when your bone marrow stops producing sufficient blood cells.2. Thus, values higher or lower than those in the reference range might or might. We conclude that infection with RSV is associated with decreased MPV and this may be clinically useful in children undergoing bronchoscopy.īronchoscopy Children Mean platelet volume Platelet count Respiratory syncytial virus.Ĭopyright © 2013 International Society for Infectious Diseases. When thrombocytopenia (low platelet count) exists with a low MPV, it can suggest that the low platelet counts are because of the bone marrow not working effectively. Larger platelets have higher thrombotic potential. A low MPV may indicate inflammatory bowel disease (IBD), such as Crohn's disease and ulcerative colitis. An MPV <8.9 fl had a sensitivity of 71% and specificity of 49% for RSV in children undergoing bronchoscopy. Mean platelet volume (MPV) is a surrogate marker of platelet activation. Abnormally low MPV values may correlate with thrombocytopenia when it is due to impaired production of megakaryocytes in the bone marrow, such as in aplastic anemia. Children with RSV undergoing bronchoscopy (n=7) also had significantly lower MPV than children without RSV (n=79) (8.8☑.0 vs. The MPV was significantly lower in patients with positive versus negative rapid RSV assays (9.7☐.8 vs. In routine clinical practice the most frequent cause of a low neutrophil count is overt or occult viral infection, including viral hepatitis. Generally, a normal RDW ranges from 12 to 15, but this number may vary depending on the lab that performs the test. As many as 20 percent of children in the United States and 80 percent of children in developing countries will be anemic at some point by. Normal RDW A normal result means that your red blood cells are similar in size. Anemia is a frequent laboratory abnormality in children.
LOW MPV LEVELS SERIES
We correlated infection with respiratory syncytial virus (RSV) with changes in mean platelet volume (MPV).Ī consecutive series of patients with positive and negative rapid RSV assays and viral cultures, as well as children under 10 years of age with bronchoscopy for pneumonia or airway obstruction, were compared. Test results appear as a percentage that lets you know whether your results are in the normal range or if your RDW is considered high or low.
To date, infections have usually been associated with elevations of the mean platelet volume.
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